Metfor XR Dosage/Direction for Use

Immediate Release Tablet: Adult dose: The usual starting dose is 500 mg twice daily or 850 mg once a day given with meals. Make dosage increases in increments of 500 mg per week or 850 mg every 2 weeks, up to a total of 2000 mg per day given in divided doses. Patients can be titrated from 500 mg twice a day to 850 mg twice a day after 2 weeks. For those patients requiring additional glycemic control, it may be given to a maximum daily dose of 2550 mg per day. Doses >2000 mg may be better tolerated given 3 times a day with meals.
Pediatric dose: The usual starting dose is 500 mg twice a day given with meals. Make dosage increases in increments of 500 mg per week up to a maximum of 2000 mg per day given in divided doses.
Extended-Release Tablet: Adult Dose: Monotherapy and combination with other oral hypoglycemic agents.
The usual starting dose is 750 mg given with evening meals. Maximum dose of up to 1500 mg given with evening meals.
After 10 to 15 days, it is recommended to check if the dose given to the patient is adequate on the basis of blood glucose measurement.
Combination with Insulin: For patients treated with combination therapy of metformin and insulin, metformin dose 750 mg with evening meals, up to a maximum dose of 1500 mg given with evening meals. Insulin dosage is adjusted on the basis of blood glucose measurement of the patient.